Evaluating the Effectiveness of Camellia Sinensis Extracts (Water and Alcoholic) and the Synergistic Effect of the Alcoholic Extract with Antibiotics Against the Salmonella Typhimurium
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Camellia Sinensis, Salmonella Typhimurium, Antibacterial Activity, Antibiotics, Synergic Effect
Abstract
This study was designed to evaluate the effectiveness of the boiling water and ethanolic extracts of Camellia sinensis with concentrations of 25, 50, 100, and 140 mg/ml and also the synergistic effect of ethanolic extract with antibiotics (AML25, IPM10, K30, S10, F300, TE30, CIP5, NA30, C10, C30, CT30, and PB300) against the Salmonella typhimurium bacteria by using the filter paper disc diffusion method. The results of this study showed the ineffectiveness of all concentrations of camellia sinensis against S. typhimurium. Also, the results showed no interaction between the ethanolic extract and antibiotics (S10, NA30, CT30, PB300), while the effect was antagonism with the antibiotics (AML25, IPM10, K30, F300, TE30, CIP5, C10, C30). This study concluded that it is possible to employ the extractions of Camellia sinensis but must be with high concentration to treat infections related to the bacteria under study instead of antibiotics, with minimal side effects.
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