The Relation Between Smoking Duration and C-Reactive Protein and White Blood Cell Count in Men
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Smoking, White Blood Cell, Reactive Protein C, Muscle Mass Index, Chronic Diseases
Abstract
Smoking is one of the highest risk factors for diseases leading to death, especially chronic diseases such as heart disease and cancer. The aim of this study was to investigate the relationship between smoking and some inflammatory factors (count of white blood cells (WBC) and C-reactive protein concentration (CRP). The study was conducted on 200 males, 100 smokers and 100 non-smokers from the region of Brak Alshatti in southern Libya, aged between 30 and 50 years old, with their body mass index (BMI) between 24.5-18.5 kg/m2. Blood samples were collected from the two groups to estimate the count of WBC and CRP concentration. A significant difference was found between the two groups in both parameters (WBC & CRP) in serum, where the mean concentrations were 10.1 ± 2.4 x 109/L & 1.8 ± 0.9 mg/L for smokers and 7.6 ± 1.9 x109/L, 1.49 ± 0.34 mg/L for non-smokers. A positive correlation was found between duration of smoking in years and WBC and CRP (R= 0.34, 0.24 and p-value = 0.001 and 0.017, respectively). In addition, positive correlation was found between the number of smoked cigarettes per day and the concentration of CRP (r = 0.4 and P = 0.0001), while it was not correlated with the number of white blood cells (R = 0.015 and P = 0.88). We conclude from this study that smoking leads to the incidence of inflammatory cases, which is exacerbated by increasing the number of smoked cigarettes per day and years of addiction to it.
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