Study of the Effect of Nigella Sativa Seeds and Oleo European Leaves on White Rats Fed A High Fat and High Sucrose Diet
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Blood Lipid, Blood Glucose, Nigella Sativa Seeds, Oleo European Leaves, Total Cholesterol
Abstract
The aim of this study was to determine the effects of the powders of Nigella sativa seeds (NSS) and Oleo europaea leaves (OEL) on blood glucose and blood lipids in high sucrose and high fat diet (HSFD)-fed white male rats after nine weeks of administration. 24 white male rats were divided into four groups each with 6 rats. At the end of this study there was an increase in Fast Blood Glucose (F.B.G.), Total Cholesterol (TC), Triglycerides (TG) and Low Density Lipoprotein-Cholesterol (LDL-Chol) levels and a decrease in High Density Lipoprotein-Cholesterol (HDL-Chol), all changes were significant except TC in HSFD-fed animals. The administration of NSS causes a decrease in F.B.G., TC, TG and LDL-Chol and an increase in HDL-Chol levels, and all changes were significant except F.B.G and TC. The administration with OEL causes a decrease in F.B.G., TC, TG, LDL-Chol, and HDL-Chol levels. All changes were significant except F.B.G.
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