The Possible Protective Role of Ginseng on Growth Performance Induced Experimentally by Bisphenol A- in Adult Male Rabbits
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Ginseng, Bisphenol A (BPA), Feed Intake, Body Weight, Organs Weight
Abstract
Bisphenol A (BPA) is a chemical material that, because of its positive characteristics, is used in polycarbonate plastic and epoxy resins. Ginseng extracts are good antioxidants. This study was carried out to investigate the possible antioxidant activity of ginseng extract on the BPA-induced effect on growth performance of adult rabbits. Twenty male New Zealand White rabbits were randomly divided into four groups: (1) control group, (2) rabbits treated with ginseng alone, (3) rabbits treated with BPA, and (4) rabbits given BPA and ginseng. The changes in body weight (BW), feed intake (FI), and drinking water throughout the 12-week experimental period. The weight of some organs, including the liver, lungs, heart, kidneys, and brain, was measured. Rabbits treated with ginseng and BPA overall mean indicated that treatment with BPA caused a significant decrease in BW, FI, and drinking water compared to control animals. Ginseng alone caused a significant increase in BW, FI, and drinking water. A similar observation was noticed with the weight of organs in different treated groups. The presence of ginseng with BPA caused a significant increase in the reduction of BW, FI, drinking water, and weight of organs due to treatment with BPA, and this means that ginseng alleviated its toxicity.
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References
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