Efficiency extent of green tea on modulation of some blood indices and lipid profiles in rabbits treated with ethanol
Abstract
Consumption of alcohol at high concentration affects several body tissues , liver, blood components, kidney and other organs. The treatment options are common nutrients such as green tea which contains vitamins, minerals and amino acids. The present study was carried out to determine the hematological and lipid profile parameter changes after administration of green tea leaves extract to rabbits treated with ethanol , Food and tap water were available ad libitum. Twenty four (24) rabbits (Orycologus caniliculus) whose weight ranged from 900- 1300 gm were used and divided into four equal groups. Control rabbits given 0.9% NaCL solution through I.P., extract group were injected with 2.5mg/ml of 20% green tea and ethanol group were injected with 20% ethanol solution in 2.5 ml, while green tea and ethanol rabbits were given 2.5 mg/ml of 2.5% green tea with 20 % ethanol simultaneously. All injection were continuously for four weeks. The observed results have shown that ethanol injected rabbits had a significant ( P< 0.05) increase in serum levels of WBC, MCV and LDL with a noticeable decrease in PTL, HTC, MCH, MCHC and HDL .The parameters were improved after administration of green tea extract, while there are no remarkable changes in red blood cells, cholesterol and triglycerides in all groups.
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