The Role Of Bee-Propolis As Antioxidants On Antioxidant Enzymes Inmale Rabbits
Abstract
Propolis has been reported to be important antioxidantThe biological effects exhibited by propolis could be related to an overall effect of the phenolic compounds present in propolis (flavonol galangin; hydroxycinnamic acids, caffeic acid, p-cumaric acid, ferulic acid and caffeic acid phenethyl ester Rabbits were orally given propolis (50 mg/kg bw) was given alone. The tested doses were given to rabbits every day for 12 weeks. The effects of propolis on plasma and testes homogenates thiobarbituric acid-reactive substances (TBARS), antioxidant enzyme glutathione (GSH), glutathione peroxidase (GPx), glutathione S- transferase (GST), catalase (CAT) and superoxide dismutase (SOD) activities Treatment with propolis caused significant (P<0.05) increase in the activity of antioxidant enzyme GSH, GPx, GST, SOD and CAT in plasma and testes homogenates compared to control. While, propolis caused a significant (P<0.05) decrease in blood plasma and testes homogenates TBARS as compared with control.
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