Investigation on some blood indices and kidney functions in patients with renal failure at Sebha Medical Center

Rehab Eissa (1) , Hind Mater (1) , Naji Laji (1)
(1) Department of Zoology, Faculty of Science, Sebha University, Libya, Libya

Abstract

This study was conducted at Sebha Medical Center in Sebha City from  the period 1/4/2018 to 30/8/2018. The study included 100 patients ( 51 male,49 females) with renal failure aged ( over18- over50 ).which compared with 54 health subjects as control group for both sexes. The aim of this study was to evaluate some of the blood  variables including WBC, RBC, HGB, MCV, MCH, MCHC and Plt and  kidney  functions which included urea, creatinine, uric acid  electrolytes ( Na, K, and Ca ) in patients with renal failure. The statistical results of the study showed a significant decrease in both platelets, white blood cell count, red blood cells, hemoglobin and mean corpuscular volume in patients with renal failure compared with control group. The data showed that the incidence of renal failure was more pronounced in females than in males and at age 20 to 40, whereas in males the age was above 50.  The results also showed a significant increase in urea, creatinine , sodium and calcium in patients with renal failure compared to control group, and for the  mean corpuscular hemoglobin concentration and mean corpuscular hemoglobin, the statistical analysis did not show the  differences between patients and control group. The present study summarized the negative effect of  renal failure in most of the blood variables and the functions of the kidney studied.

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References

[1]-Levey A., Eckardt K. and Tsukamoto Y., (2005): Kidney International, 67, 2089.

[2]-National Kidney Foundation (NKF), (2002): American journal of Kidney Disease., 39Suppl 1: S1-S266.9-10

[3]-Akkari K. B (2013): projecting requirement for and stage renal disease services. in Libya 2014-2024 inosine Jammed. B.S 5(6): 354-362.

[4]-Albert, C. E. (2001): The kidney: In Viny Kumer Abul K. Abbes and Nelson fuse, Robbins "Pathologic basis of disease" Seventh edition. Elsevier Inc.,20:960-980

[5]-Savopoulos, K. C. and Kalaitzidis, R. G. (2010): Metabolic Syndrome and Chronic Kidney Disease. European Nephrology, 4: 8–13

[6]-Boon, N. A.; College, N. R. and Walker, B. R. (2006): Davidson's Principles and Practice .20thed., Churchill, Livingstone, Philadelphia, USA.

7- الحبال، محمد جميل عبد الستار (2002): العجز الكلوي المزمن (متلازمة اليوريا مجلة أفاق طبية، العدد العاشر،

ص 66— 70

[8]-Najafi I. (2009): peritoneal dialysis in Iran and middle east peritoneal dial int. 29;217 221.

9- عزب السيد عزب، محمد عمر الباشا (2015): التغيرات الفسيولوجية المصاحبة للفشل الكلوي عند مرضي الفشل الكلوي المزمن بمستشفيي الزهراء لعلاج وجراحة الكلى، مجلة كليات التربية، العدد الثالث، 158— 173.

[10]-Tietz, N.W. (1995): Clinical guide to laboratory tests, 3r.Ed., Philadelphia, Saunders Company.

[11]-Khalidah S. Merah and Suha Falih Hasson (2015): The Biochemical Changes in Patients with Chronic Renal Failure, International Journal of Pharma Medicine and Biological Sciences Vol. 4, No. 1.

[12]-Deighan, C.J., CA slake, M.J &McConnell, M., (2000): Atherogenic lipoprotein phenotype in end stage renal failure: Origin and extent of small dense low-density lipoprotein formation American Journal for Kidney Disease, 35: 852–862.

[13]-Kadhum, W.A., (2008): Serum lipid profile in renal failure patients, unpublished master thesis, Kufa university, 18 –

[14]-Costa, E.; Rocha, S.; Rocha-Pereira, P.; Castro, E.; Miranda, V.; Faria, M. D.Sc.; Loureiro, A.; Quintanilha, A.; Belo, L. and Santos-Silva, A. (2008): Band 3 Profile as a Marker of Erythrocyte Changes in Chronic Kidney Disease Patients. The Open Clinical Chemistry Journal, 1: 57-63.

[15]-Hsu, C-Y.; Bates, D. W; Kuperman, G. J. and Curran, G. C. (2001): Relationship Between Hematocrit and Renal Function in Men and Women Kidney International, 59: 725–731.

[16]-Basara, A.; Girone, J. F. Erslev, A. and Caro, J. (1989): Recent Development sin The Anemia of Chronic Renal Failure. Sem Dial, 2: 87-97

[17]-Al-Hilali, N.; Al-Hamoud, H.; Ninan, V. TT.; Namport M. R.; Publicly, M. A. and Johny, K. V. (2007): Does Parathyroid Hormone Affect Erythropoietin Therapy in Dialysis Patients? Mediacrat, 16(1): 63-67.

[18]-Albuera, M.; Remzi, G. and Boccardo, P. (2009): Treatment of Bleeding in Dialysis Patients. Semin Dial, 22(3): 279–286-.

[19]-Altun, B.; Arici, M.; Handroll, C.; Uslan, C.; Erdem, Y.; Yasavul, U.; Torgan, C.; Caglar, S. and Kiraly, S. (1999): Serum Thrombopoietin Levels in Hemodialysis Patients: Involvement of Arteriovenous Fistula. Nephron Dial Transplant, 14: 2173–2177

[20]-Kopple, J. D.; Kalantar-Zadeh, K. and Mehrotra, R. (2005): Risks of Chronic Metabolic Acidosis in Patients with Chronic Kidney Disease. Kidney International, 67:21.

[21]-Yoon, J. W.; Gollapudi, S.; Pahl, M. V. and Vaziri, N. D. (2006): Naive and Central Memory T-cell Lymphopenia in End-Stage Renal Disease. Kidney

]22[— فلفل، عادل عبادي. :( 2012) بعض المؤشرات المناعية والجرثومية دي مرضي الفشل الكلوي المزمن رسالة

ماجستير، جامعة بابل، كلية العلوم، العراق.

[23]-Azab Elsayed Azab1, Ata Sedik Ibrahim Elsayed, (2016): Correlation between Chronic Kidney Diseases and Hematological Data in Sabratha Hospital in Libya, Sch. J. App. Med. Sci., 4(12B):4298-4306.

[24]-Clase C., Gary A. and Kibera B., (2004) BMJ, 329, 912.

[25]-Al-Abachi S. Z., Mustafa L. A., Hassan D. S. K. and Al-Hadadi A. (2012): Study of some biochemical changes in some of patients with chronic renal failure. Iraqi National C.Chem., 46:270-280.

]26[- سكينة بوزيد سعيد بوزيد وسماء محمد احمد خماح (2019): دراسة بعض التغيرات الفسيولوجية المرافقة للفشل الكلوي المزمن وتأثيراتها السلبية على مرضى الفشل الكلوي، مجلة كليات التربية العدد (14) الزاوية جامعة

الزاوية، 331— 346.

Authors

Rehab Eissa
Hind Mater
Naji Laji
Eissa, R. ., Mater , . H. ., & Laji, N. . (2019). Investigation on some blood indices and kidney functions in patients with renal failure at Sebha Medical Center. Journal of Pure & Applied Sciences , 18(2), 67-72. https://doi.org/10.51984/jopas.v18i2.341

Article Details

How to Cite

Eissa, R. ., Mater , . H. ., & Laji, N. . (2019). Investigation on some blood indices and kidney functions in patients with renal failure at Sebha Medical Center. Journal of Pure & Applied Sciences , 18(2), 67-72. https://doi.org/10.51984/jopas.v18i2.341

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