Vascular calcification: Role of vascular smooth muscle cells and its regulation by microRNA

Authors

  • Abeer H. Amer
  • Manal. F. Yaya
  • Hasem H. Abdalla

DOI:

https://doi.org/10.51984/jopas.v20i1.985

Keywords:

Calcification, MicroRNA, Muscle cells, Vascular smooth

Abstract

In this review, the aim is to discuss the pathological development of vascular calcification including a brief description of arterial wall structure and function, the development of atherosclerosis, highlighting  normal physiological and vascular calcification with particular emphasis on their common characteristics, critically review the recent findings implicating the role of vascular smooth muscle cells in the pathogenesis of the calcification process including the role of microRNAs in regulation of these cells phenotype as a target to control cardiovascular calcification.  

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Published

2021-01-28

Issue

Section

Articles