Creatine Kinase (CK) Activity Increased in Obese Women in Region of Brak Ashati, Libya
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Body Mass Index (BMI), Creatin Kinase (CK), CKMB, Obesity
Abstract
Creatine kinase (CK) plays an important role in cellular metabolism. There is a high activity of the enzyme in skeletal muscle fibers, especially type II fibers. The aim of the study was to investigate whether the CK enzyme activity in serum is related to obesity in women. We analyzed 61 samples of women in the region of Brak, Libya, aged 21 to 69 years, divided into two groups according to their body mass index (BMI): obese and lean groups. Blood samples were collected to measure the activity of CK and CK-MB in serum. A 2-sample t-test was applied to show the difference, and Pearson correlation was used to assess the correlation between serum CK and body mass index (BMI). CK activity was significantly higher in obese women compared with lean ones, and CK activity positively correlated with BMI. In conclusion, CK activity was affected by obesity and BMI.
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