The Frequency of ABO And Rhesus Blood Groups Phenotypes, Genotypes From Sebha City of Libya
Article Sidebar
-
ABO Blood-Group System, Alleles Frequencies, Genotype Frequencies
Abstract
The frequency of ABO and Rhesus blood groups vary geographically, ethnically and from one population to another. Some variations may even occur within one ethnic group and within one small country. This study was conducted to determine the frequency of ABO and Rhesus blood groups phenotypes, genotypes and alleles in Sebha city.A total of 527 samples were randomly collected and tested for ABO and Rhesus blood groups antigens using open slide methods. The frequencies of ABO and Rhesus blood groups phenotypes were expressed in percentages and the Hardy-Weinberg Law was used to determine allele and genotype frequencies.Results: Blood group (O) is the most frequented group (42%) of the totally, followed by group (A) (28%) and group B (23%). Least prevalent blood group was AB (7%). Rh D positive prevalence was 81.7% and 18.2% persons were Rh negative. The allele frequencies of IO, IA, and IB in the total sample were found to be, 0.649, 0.194, and 0.160 respectively. The order of ABO blood group allele frequencies was IO > IA > IB in the overall samples. ConclusionIn present study blood group O was the commonest followed by group A. the order of the frequencies of ABO blood group alleles is IO > IA > IB. Therefore, the findings of this study can be used as a baseline for the genetic diversity of the study area as a reference for Libyan ABO blood group phenotypes and genotypes studies.
Full text article
References
[1]-Shruti S RG, Vijay K.: ABO, Rhesus Blood Group And Allele Frequency In And Around Raipur (Chattisgarh State), India. Int J Cur Res Rev 2015, 7(17):52-58.
[2]-Storry JR,Castilho L,Chen Q,Daniels G,Denomme G,Flegel WAet al(2016)International society of blood transfusion working party on red cell immunogenetics and terminology: report of the Seoul and London meetings. ISBT Science Series.11(2) 118–122
.[3]-Rai V, Kumar P Genetic analysis of ABO and Rh blood groups in Brahmin Population of Uttar Pradesh, India. Nature Proceedings 2011, 21(4):126_232.
[4]-Mandal S: Fundamentals of Human Genetics, 2nd edn. New Delhi, India: New Central Book Agency (P) LTD; 2002.
[5]-Rehman A KM, Ashraf M, Malik S, Saeed M A, Rafique A, et al: ABO and Rhesus blood groups in Pakistan population. Professional Medical Journal2005, 12(4):368-371.
[6]-Hanania S, Hassawi DS, Irshaid NM.: Allele frequency and molecular genotypes of ABO blood group system in a Jordanian population.MedSci 2007, 7((1) ):51-58.
[7]-Dar N.J SA, Dar F A, : Distribution of ABO blood groups and Rh (D) factor among the Brahmin and Kushwaha populations of Jhansi District (U.P). Anthropologist2010, 11(4):305-306.
[8]-Rudman SV: The ABO and H blood group system. In text book of blood bank¬ing and transfusion medicine. In., 2nd ed edn: Saunders publication; 2005: 73-74.
[9]-Abdularahman BO, Sameer A, Salwa IH, Qamre A,Mohammad ZA, Absarul H, Waseem A, Ghazi A. : Allelic variance among ABO blood group genotypes in a population from the western region of Saudi Arabia Blood Res 2016, 51:274-278.[10]-Alia EM, Asmaa MS, Maisam BNA, Noor JA. : Gene frequencies of ABO and rhesus blood groups in Sabians (Mandaeans), Iraq.Baghdad Science Journal 2014, 11(2).
[11]-Al-Bustan S, El-Zawahri M, Al-Azmi D, Al-Bashir A: Allele Frequencies and Molecular Genotyping of the ABO Blood Group System in a Kuwaiti Population.International Journal of Hematology 2002, 75(2):147-153.
[12]-Yassin WD: Frequency of ABO and Rhesus (RhD) Blood Group Alleles Among Students of Oromo Ethnic Group Belonging to Arsi, Guji, and Borena Clans in Robe College of Teachers Education [dissertation]. Ethiopia: HARAMAYA UNIVERSITY; 2013.
[13]-Abass TA, Olubukola AO , Kehinde MA , Oluyinka A , Bolaji FO. : Gene frequencies of ABO and Rh blood groups in Nigeria: Areview.The Egyptian Journal of Medical Human Genetics 2017, 18:205-210.
[14]-Zahid H YA, Uwingabiye J, El Khazraji A, El Hadef R, Messaoudi N: Phenotypic and allelic distribution of ABO And Rh-D blood Groups in Blood Transfusion Center of Avicenna Military Hospital, Marrakech, Morocco.International Journal of Medicine & Health Research 2016, 1( 2): 1-9.
[15]-Zaoui S, Feingold j, Meguenni k, Chabane SD. : ABO and rhesus blood groups system in Tlemcen population, West Algerian. Biologie & Santé 2007, 7(1).
[16]-Abraham H, Ayalew T M, Fessahaye A, Fasil T, Kifle W, Makonnen A, Yoseph M, Solomon T, and Gemeda A.: Hematoimmunological profile at Gilgel Gibe Field Research Center, south west Ethiopia.Ethiopian Journal of Health Science 2012, 22(1):39_50.
[17]-Rai V, Kumar P: The incidence of ABO blood group in Muslim population of Uttar Pradesh, India.Journal of Applied Biological science 2010, 36(2):191-195.
Authors
This work is licensed under a Creative Commons Attribution 4.0 International License.
In a brief statement, the rights relate to the publication and distribution of research published in the journal of the University of Sebha where authors who have published their articles in the journal of the university of Sebha should how they can use or distribute their articles. They reserve all their rights to the published works, such as (but not limited to) the following rights:
- Copyright and other property rights related to the article, such as patent rights.
- Research published in the journal of the University of Sebha and used in its future works, including lectures and books, the right to reproduce articles for their own purposes, and the right to self-archive their articles.
- The right to enter a separate article, or for a non-exclusive distribution of their article with an acknowledgment of its initial publication in the journal of Sebha University.
Privacy Statement The names and e-mail addresses entered on the Sabha University Journal site will be used for the aforementioned purposes only and for which they were used.