Potentiometric Studies on Stability Constant of The Complexes of Someessential Transition Metal Ions With L-Valine
Article Sidebar
-
Metal ions, Potentiometric method, Stability constant, Metal complexes, L-Valine
Abstract
The interaction of Co (II), Ni (II) and Cu (II) metal ions and the biologically important amino acid L-Valine, (2-amino-3-methyl butanoic acid) have been investigated. The potentiometric technique was used to study these intraction at 313.15 ± 0.1 K in the absence and in the presence of ionic strength of 0.1 M (NaCl) in aqueous medium. The data obtained under the above experimental conditions were used to evaluate the values of proton-ligand and metal-ligand stability constants using Irving-Rossotti titration technique. The formation of the 1:2, (M:L), binary complexes are confirmed by the corresponding pH titration curves. The values of logK and log? were calculated and found in the order of copper (II) > nickel (II) > cobalt (II).
Full text article
References
[1]-M. Cempel, Nikel, G. , "Nickel: A Review of Its Sources and Environmental Toxicology," Polish Journal of Environmental Studies, vol. 15, pp. 375-382, 2006.
[2]-Q. A. Acton, Branched-Chain Amino Acids: Advances in Research and Application: ScholarlyEditions, 2013
[3]-R. Alexandrova, Rasshkova, G., Alexandrov, I., Tsenova, W., Tudose, R. and Costisor, O. , "Briefly about copper," Experim. Pathol. and Parasitol., vol. 2003, pp. 1311, 6851, 2003.
[4]-B. G. Malmström and J. Leckner, "The chemical biology of copper," Current Opinion in Chemical Biology, vol. 2, pp. 286-292, 1998/04/01/ 1998.
[5]-N. Coleman, et al., The Toxicology of Essential and Nonessential Metals: Lulu.com, 2017.
[6]-R. M. Smith, et al., "Prediction of stability constants. II. Metal chelates of natural alkyl amino acids and their synthetic analogs," Inorganica Chimica Acta, vol. 103, pp. 73-82, 1985/09/02/ 1985.
[7]-A. Gergely, et al., "Thermodynamic relations of parent and mixed complexes of asparagine and glutamine with copper(II)," Journal of Inorganic and Nuclear Chemistry, vol. 37, pp. 551-555, 1975/02/01/ 1975.
[8]-"IUPAC-IUB Joint Commission on Biochemical Nomenclature (JCBN). Nomenclature and symbolism for amino acids and peptides. Recommendations 1983," Biochemical Journal, vol. 219, pp. 345-373, 1984.
[9]-C. J. Lynch and S. H. Adams, "Branched-chain amino acids in metabolic signalling and insulin resistance," Nature Reviews Endocrinology, vol. 10, p. 723, 2014.
[10]-B. E. Leach and R. J. Angelici, "Stereoselective interaction of optically active amino acids and esters with (L;valine-N-monoacetato)copper(II)," Journal of the American Chemical Society, vol. 91, pp. 6296-6300, 1969/11/01 1969.
[11]-Y. Masaaki, Shingo, Kikuchi,Jun, Sen, Toshimichi, Kamei, Norihito, Doki, "Cu(II) Complex of L-Leucine Favor a Different Typeof Crystal Structure from Cu(II)-L-Val and Cu(II)-L-Ile," Advances in Chemical Engineering and Science, vol. 6, p. 5.
[12]-V. A. a. M. Davankov, P. R., "Stereoselectivity in bis(α-amino-acid)copper(II) complexes," Journal of the Chemical Society, Dalton Transactions, vol. 168, p. 1012, 1972
Authors
This work is licensed under a Creative Commons Attribution 4.0 International License.
In a brief statement, the rights relate to the publication and distribution of research published in the journal of the University of Sebha where authors who have published their articles in the journal of the university of Sebha should how they can use or distribute their articles. They reserve all their rights to the published works, such as (but not limited to) the following rights:
- Copyright and other property rights related to the article, such as patent rights.
- Research published in the journal of the University of Sebha and used in its future works, including lectures and books, the right to reproduce articles for their own purposes, and the right to self-archive their articles.
- The right to enter a separate article, or for a non-exclusive distribution of their article with an acknowledgment of its initial publication in the journal of Sebha University.
Privacy Statement The names and e-mail addresses entered on the Sabha University Journal site will be used for the aforementioned purposes only and for which they were used.