Effect Of Moringa Oleifera Extract On Some Sperm Parameters And Testis In Diabetic Rats
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Moringa Oleifera, Spermatogenesis, Sperm Count, Abnormal Sperm
Abstract
This study aims to demonstrate the effectiveness and ability of the methanolic extract of Moringa oleifera (M. oleifera) leaves to improve some sperm parameters and testis in diabetic rats. Twenty healthy adult male Wistar rats divided equally into 4 groups of (n = 5) were used in this investigation. The first group represents the negative control, while the second group is the positive control, whereas the following two groups represent the treated groups of M. oleifera leaves with a concentration of 300 mg/kg and 600 mg/kg for 4 weeks. At the end of the experiment, the rats were anesthetized, and sperm was collected from the epididymis to calculate their numbers and abnormalities in them by light microscope. Meanwhile, the testis was extracted for histological study. The totals of treatment with the extract in the M. oleifera groups showed a significant decrease in the level of fasting sugar (P < .00). The number of sperm was significantly increased (P < .01), whereas there was a significant decrease in the number of abnormal sperm (P < .00). The histological study showed improvement in the process of sperm production. From this study we conclude the ability of the M. oleifera leaf extract to improve some sperm parameters and histology of the testis in diabetic rats.
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References
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