Assessment of Non-Alcoholic Fatty Liver Disease in Type 2 Diabetic Patients From South of Libya
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Diabetes mellitus, Fatty liver, Libya, NAFLD, Ultrasonography
Abstract
Non-alcoholic fatty liver disease (NAFLD) is emerging as one of the most common chronic liver diseases worldwide; however, no published work has been found about its prevalence among Libyan diabetics or general population. The present study aimed to determine the magnitude of NAFLD among Type 2 diabetic patients (DM) from south of Libya. Eighty- five (85) Type 2 diabetic patients (35 males & 50 females) attending Traghen Hospital (South of Libya) were utilized in this cross-sectional study. All the participants were examined for the presence of fatty liver via Ultrasonography. Biochemical parameters (Fasting Blood Sugar , Total Cholesterol , Triacylglycerol , Alanine aminotransferase , Aspartate aminotransferase ) were also measured. Ultrasonography examination showed that 40% of Type 2 DM patients included in this study had non-alcoholic fatty liver disease; of whom 56%, 38%, and 6% had mild, moderate, and severe grade fatty liver respectively. Serum Triacylglycerol and fasting blood sugar were significantly higher (P = 0.007, 0.043 respectively) in type 2 DM patients with NAFLD compared with those without NAFLD; however, other biochemical parameters showed no significant differences (P˃0.05). The distribution of NAFLD among Type 2 DM patients was significantly associated with duration of diabetes condition, and serum level of Triacylglycerol (P = 0.018, 0.033 respectively). We conclude that diabetic patients with hypertriglyceridemia, especially those with long duration of diabetes are highly advised to undergo ultrasonography examination for early detection of fatty liver disease.
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